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Boosting the volume of the hormone serotonin diminishes the thoughts of anxiety, trouble sleeping, lack of desire for food, strain, and major depression that often go with lower amounts of serotonin. St. st. John's Wort side effects have been repeatedly when compared with certain SSRIs for instance Zoloft along with Prozac and viewable very similar results without the majority of the negative side affects which might be related to these medications possibly the higher price tags that will associate with these people.